Several Bulldogs' players are expected to be questioned by police in Sydney on Wednesday, with a number of the rugby league stars likely to undergo DNA testing once all interviews are over.

Several of the club's players have been accused of gang raping a 20-year-old woman at the Pacific Bay resort at Coffs Harbour on February 22 after a National Rugby League pre-season match in the northern NSW city.

Strike Force McGuigon investigators will begin further interviews with players on Wednesday in connection with the incident, police said.

Coffs Harbour Acting Superintendent Matt Sponberg said it was unlikely all of the players would be questioned.

He was unable to confirm how many of the 25 players in the squad would be involved, or whether individual players were being zeroed in on.

"It just depends how many of them have a start or may provide some assistance. It just depends if they think they (police) need to interview them," he said.

Supt Sponberg said the interviews were likely to take "a few days".

Despite the high-profile nature of the case, he said the investigation would not be accelerated.

"It's high-profile but for us it's just an investigation ... we're treating it normally," he said.

"There's no pressure to do it quicker."

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