A ruthless Gold Coast kicked the boot into an injury-ravaged Brisbane with an emphatic 34-14 victory in Friday night's NRL clash at Skilled Park.

The Titans kept their perfect home record intact this season and consigned the Broncos, missing seven first-graders, to a sixth loss from their past seven matches.

Brisbane were always going to struggle without injured Origin stars Darren Lockyer, Israel Folau, Karmichael Hunt, Peter Wallace and Sam Thaiday.

Tonie Carroll and Nick Kenny were also missing from a side that has now conceded 251 points in their last seven games.

Rookie halfback Ben Hunt, 19, tried hard for the visitors but it was an uphill battle against a well-drilled Titans, missing only five-eighth Mat Rogers (groin), in front of a 26,336-strong crowd.

Brisbane opened the scoring through a Corey Parker penalty goal in the sixth minute after Anthony Laffranchi was punished for a lifting tackle on Aaron Gorrell.

But the Titans then raced in tries to Mark Minichiello (11m), Ashley Harrison (14m), Michael Henderson (20m) and Kevin Gordon (30m) to hold a commanding 22-2 halftime lead.

The mercurial Prince had a hand in every one of those tries.

He threw a neat inside ball to William Zillman to set up Minichiello, gave the last pass for Harrison, put in a grubber that bounced off the post for Henderson to score and launched a terrific cut-out missile for Gordon's try.

The slaughter continued in the second half as Prince bagged a soft try off a Preston Campbell kick and Esi Tonga crossed out wide with Brisbane's defensive line in tatters.

Gold Coast led 34-2 and the contest was over.

Brisbane winger Anthony Winterstein scored a brace of tries in a 12-minute period in the second half to bridge the deficit to 34-14.

A brilliant Hodges flick pass set up Dale Copley for a try in the dying seconds as the Titans finished 34-18 victors.

The Broncos have their work cut out if they're to avoid missing the finals for the first time since 1991.

Titans coach John Cartwright was delighted with his third-placed team's effort over 60 minutes but bemoaned their drop in intensity the final quarter of a predictable match.

"I thought the first 40 minutes was as good as we've put together all year," Cartwright said.

"There were some good tries scored, nothing flash about it, but we stuck to a pretty basic plan.

"The back 20 minutes was disappointing. We missed a lot of tackles and probably gave them some points they didn't deserve."

While not looking for any excuses for the late fade, Cartwright pointed to the second half loss of Harrison (ribs), Minichiello (knee) and hooker Nathan Friend (ankle).

With more than $2 million of talent watching from the sideline, the Broncos lacked the experience to handle the big occasion but it could have been much worse.

"I was really pleased that we didn't throw the towel in," Henjak said.

"They (the Broncos) just kept plugging away even though some things were going against them.

"They tried to stay in the fight in the second half which was really positive.

"I thought some of those young blokes did really well in the second half."

Cartwright made special mention of the courageous Friend, who made 29 tackles before leaving the field with a bad limp after being in doubt all week.

"When it really counted he never showed any sign of pain or discomfort," the coach noted.

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