Scotland's rugby players head to Twickenham on Sunday looking to foil the Grand Slam hopes of fierce rivals England as a trio of challengers hope the 2003 world champions slip up in the fourth round of the Six Nations.

England took maximum points from the opening three matches to be on course to win their first Six Nations title in eight years.

The Scots, meanwhile, are not off the mark in this season's competition and are without an away win over the English since 1983.

However, if there's a fixture to bring the best out of the Scots, it's the Calcutta Cup.

"The players have got to be inspired by the stadium and also by the team that they're playing against - they're right at the top of their game," said Scotland coach Andy Robinson, a former England player who coached the team during a disastrous spell from 2004-06.

"We have the personnel who can deal with it, but we have to be right at the top of our game. The record books show what a special achievement it would be for the Scotland team to win on Sunday."

Scotland have beaten England at Twickenham just four times since they first met there 100 years ago but if Robinson's men do grab a rare victory in southwest London, they won't be the only ones celebrating on Sunday night.

Wales, Ireland and France - the past three winners of the northern hemisphere competition - are all on four points, two behind England, and still have hopes of pipping Martin Johnson's side to the title.

Wales host Ireland on Saturday, hours after France visit Italy, who are fighting with Scotland to avoid a last-place finish.

England's team is unlikely to be much changed from the 17-9 win over France on February 26 - a match most pundits branded a Grand Slam decider.

That should mean Toby Flood, arguably the player of the competition so far, starting again at flyhalf ahead of Jonny Wilkinson, England's World Cup-winning No.10 from eight years ago.

"The best evidence you can have (that it was the right decision) is looking at it results-wise and flow-wise," Wilkinson said.

"The relationship Floody has created and managed to put in place with the other guys, the way they work together and the way they link, wasn't quite there when I was playing."

Scotland made four changes in personnel and a positional switch for the match, with winger Simon Danielli, centre Joe Ansbro, scrumhalf Rory Lawson and flanker Nathan Hines all returning and Kelly Brown moving from the side of the scrum to No.8.

The French are expected to bounce back from their defeat as they average nearly 50 points per game in Italy.

Fullback Maxime Medard, flanker Julien Bonnaire and prop Sylvain Marconnet were recalled by Les Bleus coach Marc Lievremont, while Morgan Parra has been summoned to replace scrumhalf Dimitri Yachvili, who pulled out on Thursday with a thigh injury.

Italy coach Nick Mallett made seven changes to the side beaten by Wales last time out, one being Luciano Orquera in for Kristopher Burton at flyhalf.

James Hook is back at flyhalf for Wales, replacing Stephen Jones, following the return from injury of centre Jonathan Davies. The only other change by the Welsh, who have won their past two games, is Leigh Halfpenny replacing Morgan Stoddart on the wing.

The Irish are unchanged.

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