Gold Coast coach John Cartwright says his players' recent massive upset against the Roosters is proof anything is possible if they turn up on the night.

It will take that performance - inspired by a magnificent second-half comeback - and more to pull off what would be an even bigger shock against Melbourne at Olympic Park on Friday night.

There's no tougher assignment in the NRL than playing the Storm at home.

They rarely lose.

But Cartwright, despite again having to make changes because of injury and suspension, said his players could draw from the round 18 effort against the Roosters who were leading the competition at the time.

"There's no argument it's the toughest game in the competition because they've got the best home record of any side in the premiership," said Cartwright.

"I'm not sure what their record is there but I think they've only lost once in two years.

"What people expect of us doesn't really come into it with what they (players) expect of themselves.

"They're professional footballers and proud guys.

"We had a win against the odds against the Roosters who were leading the comp. We've got to draw from the experience and know anything is possible.

"It's all about turning up and aiming up.

"That performance against the Roosters was only three weeks ago and we put our best 40 minutes of the season together in the second half."

Former Origin and Test forward Brad Meyers returns from playing two weeks in the Queensland Cup with Ipswich.

"It was a form issue," said Cartwright, explaining Meyer's fall from the NRL.

"We've had some injuries and Brad's got another opportunity.

"It's good to have a guy of his experience to call on.

"Brad's a very professional player and he accepted he had some form issues to work on.

"He's coming off a knee reconstruction which can take 12 months to fully get up.

"He's had an up and down year.

"He started very well and he can still finish the year well."

Melbourne will be fired up after missing a chance to join Manly on top of the ladder, losing to the Warriors 8-6.

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