North Queensland lock Luke O'Donnell's minute of madness in the Cowboys' 23-16 loss to the Wests Tigers looks to have cost him at least three weeks on the sidelines.

O'Donnell has been charged by the NRL judiciary with a grade two dangerous contact offence after an ugly tackle on Tigers fullback Beau Ryan which saw his neck twisted.

The tackle prompted a minor melee and the Australian representative was sin-binned just before half-time.

O'Donnell will be out for three weeks if he enters an early guilty plea but risks fours weeks if he fights the charge and loses.

It was a fiery night for the 29-year-old who was penalised four times during the game including one incident in which he launched a spray at referee Gavin Badger.

Two charges came out of South Sydney's 28-10 win over Newcastle with Rabbitohs utility Ben Lowe looking at a two-match ban for a grade two careless high tackle if found guilty.

Knights centre Junior Sau faces a one-match ban for a grade one dangerous contact to knee or legs.

Dragons prop Michael Weyman also risks a one-match suspension for a grade one striking charge during his side's 34-16 win over Brisbane.

Manly's Test frontrower Brent Kite will miss Monday's game against Melbourne if he enters an early guilt plea for a grade one careless high tackle on Cronulla winger Blake Ferguson.

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